Jenner, who is pregnant with her second child by rapper Travis Scott, hit the record despite not posting as much on her verified account since the tragedy at Scottâ€™s Astroworld music festival that left ten people dead many more injured.
As of Thursday morning, Jennerâ€™s most recent post was a set of images she shared of her pregnant belly just after the start of the new year.
However, the latest report also means Jenner is ahead of Lionel Messi (300m) and Dwayne Johnson (289).
The only women close to Jenner are Ariana Grande, Selena Gomez.
They are both tied on sixth and seventh with 289 million followers.